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. 2021 Apr 22;11:646737. doi: 10.3389/fonc.2021.646737

Table 1.

Patient baseline characteristics and tumor characteristic.

Before PSM After PSM
Characteristic LRH (n = 68) ORH (n = 358) P-value LRH (n = 57) ORH (n = 57) P-value
Age (years) 56.0 (36.0–78.0) 60.0 (27.0–86.0) 0.099 56.0 (36.0–78.0) 59.0 (34.0–77.0) 0.910
Gender (male/female) 54/14 320/38 0.021* 49/8 50/7 0.782*
Maximum tumor size (cm) 1.5 (0.6–10.0) 2.0 (0.5–13.0) <0.001 1.5 (0.6–4.5) 1.7 (0.8–4.5) 0.433
No. of tumors 1.0 (1.0–4.0) 1.0 (1.0–6.0) 0.051 1.0 (1.0–4.0) 1.0 (1.0–2.0) 0.487
Previous surgical approach
Laparoscopic 16 21 <0.001* 7 5 0.542*
Open 52 337 50 52
No. of previous surgery 1.0 (1.0–2.0) 1.0 (1.0–5.0) 0.408 1.0 (1.0–2.0) 1.0 (1.0–3.0) 0.182
Tumor location
Anterolateral 53 179 <0.001* 43 47 0.358*
Posterosuperior 15 179 14 10
HBV (Y/N) 63/5 325/33 0.621* 52/5 53/4 1.0*
Child–Pugh grade (A/B) 68/0 357/1 1.0* 57/0 57/0 1.0*
Liver cirrhosis (Y/N) 35/33 180/178 0.857* 31/26 31/26 1.0*
TB (μmol/L) 11.35 (2.7–37.7) 13.0 (3.1–37.5) 0.120 11.2 (2.7–37.7) 13.2 (4.7–36.4) 0.134
ALT (U/L) 20.5 (6.0–49.0) 21.0 (5.0–219.0) 0.474 20.0 (6.0–43.0) 21.0 (8.0–86.0) 0.512
Albumin (g/L) 45.0 (30.0–53.0) 44.0 (26.0–69.0) 0.742 45.0 (30.0–53.0) 46.0 (36.0–69.0) 0.345
PT (s) 11.6 (10.0–14.0) 11.5 (9.6–15.3) 0.752 11.5 (10.0–14.0) 11.5 (10.2–13.7) 0.986
AFP (ng/mL)
<20 41 236 0.500* 36 36 0.188*
20–400 17 84 12 16
≥400 8 28 7 2
Tumor capsule
None and partial 42 202 0.414* 33 29 0.452*
Complete 26 156 24 28

Values are median (range).

*

Pearson χ2 tests or Fisher's exact test, as appropriate.

Mann–Whitney U-test (Wilcoxon rank sum W-test).

PSM, propensity score matching analysis; LRH, laparoscopic repeat hepatectomy; ORH, open repeat hepatectomy; HBV, hepatitis B virus; TB, total bilirubin; ALT, alanine transaminase; PT, prothrombin time; AFP, α-fetoprotein; Y, yes; N, no.