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. 2021 Apr 22;14:658465. doi: 10.3389/fnmol.2021.658465

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Copyright © 2021 Bartsch, von Cramon, Gruber, Heinemann and Behr.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LTP in stressed rats is expressed pre- and postsynaptically. (A) Quantification of paired-pulse index (PPI). Circles depict the mean value of single neurons before (base) and after (post) LTP induction, columns represent mean ± SEM of all recorded neurons. Paired-pulse index (PPI) does not change after induction of LTP in stressed rats (control: n = 6/5, paired Student’s t-test, p = 0.50; stress: n = 5/5, paired Student’s t-test, p = 0.28). (B) Plot relating the ratio of the coefficients of variation (CV) squared to the ratio of the mean EPSP amplitudes in stressed rats. Classically, for a single cell the locus for potentiation is postsynaptic when data is on horizontal line, presynaptic when above the identity line or both when between the horizontal and the identity line.