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. 2021 Apr 22;12:651475. doi: 10.3389/fimmu.2021.651475

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Copyright © 2021 Li Yim, Ferrero, Maratou, Lewis, Royal, Tough, Larminie, Mannens, Henneman, de Jonge, van de Sande, Gerlag, Prinjha and Tak

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cellular composition estimation. Cellular proportions were estimated for 64 cell types using the xCell algorithm. Of these, 6 cell types were found to be significantly different when comparing SJC66_high with SJC66_low. Visualized as scatter- and cross-bar plots are the significantly differentially represented cell types, namely the neurons, conventional dendritic cells (cDC), dendritic cells (DC), immature dendritic cells (iDC), megakaryocytes, and platelets.