Table 2.
Association between survival and IASLC/ATS/ERS classification of dominant tumor (DT).
| Variables | Grade (N = 149); % | Low (N = 32); % | Intermediate (N = 87); % | High (N = 30); % | p value |
|---|---|---|---|---|---|
| 5-year overall survival (%) | 88.6 | 96.9 | 94.3 | 63.3 | < 0.001 |
| 5-year disease-free survival (%) | 78.5 | 100 | 87.2 | 30.0 | < 0.001 |
| Follow-up period (months) | 80.4 ± 34.8 | 66.3 ± 23.2 | 89.5 ± 36.8 | 69.0 ± 31.6 | 0.001 |
| Disease-free duration (months) | 69.4 ± 37.1 | 66.3 ± 23.2 | 80.9 ± 37.9 | 39.6 ± 29.5 | < 0.001* |
| Total recurrence, no. | 44 (29.5) | 0 | 20 (23.3) | 24 (80.0) | < 0.001 |
| Patterns of recurrence | 0. 595** | ||||
| Local only | 13 (29.5) | 0 | 7 (35.0) | 6 (25.0) | |
| Distant only | 12 (27.3) | 0 | 6 (30.0) | 6 (25.0) | |
| Local + Distant | 19 (43.2) | 0 | 7 (35.0) | 12 (50.0) |
*ANOVA Test.
**Chi-Square tests, compared between intermittent and high grade groups.