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. 2021 Apr 22;12:671966. doi: 10.3389/fimmu.2021.671966

Table 1.

Summary of ILC2 phenotypes.

Mouse Human
Lung Intestine Skin Liver Fat Blood
CD127 + + + + + +
CD90 + + + + +
CD25 + + + + + +
CD103 ND ND + ND ND
IL-18Rα + +
ST2 + low +/low + +
IL-25R low + +/low ND
CRTH2* +
CD161* +
GATA3 + + + + + +

“+”, expressed; “−”, not expressed; “low”, expressed at low levels; “+/low”, various reports exist; “ND”, not determined. *human ILC2 markers. Human ILC2 phenotype is based on peripheral blood ILC2s.