Table 3.
Univariate and Multivariate Analysis for Risk of UC-Related Hospitalization and Colectomy in 291 Patients with UC Diagnosis between 2000 and 2018
| Factor | Univariate analysis |
Multivariate analysis |
||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| UC-related hospitalization | ||||
| Male sex | 1.41 (0.86–2.33) | 0.18 | - | - |
| Age at diagnosis (< 40 yr) | 1.14 (0.69 –1.87) | 0.61 | - | - |
| BMI (per 1 unit increase) | 1.00 (0.93–1.08) | 0.93 | - | - |
| Ever/current smoker | 0.57 (0.21–1.56) | 0.27 | - | - |
| Extensive colitis | 2.83 (1.66–4.82) | < 0.01 | 2.82 (1.66–4.82) | < 0.01 |
| Extraintestinal manifestation | 1.79 (0.91–3.52) | 0.09 | 1.63 (0.83–3.21) | 0.16 |
| Calendar period of diagnosis in 2000-2009 | 1.64 (1.00–2.71) | 0.05 | 1.70 (1.03–2.81) | 0.04 |
| Colectomy | ||||
| Male sex | 1.23 (0.45–3.30) | 0.69 | - | - |
| Age at diagnosis (< 40 yr) | 0.46 (0.16–1.35) | 0.16 | - | - |
| BMI (per 1 unit increase) | 1.00 (0.87–1.15) | 1.00 | - | - |
| Ever/current smoker | 0.71 (0.09–5.44) | 0.74 | - | - |
| Extensive colitis | 2.14 (0.77–6.00) | 0.10 | 1.96 (0.69–5.51) | 0.20 |
| Extraintestinal manifestation | 0.50 (0.07–3.80) | 0.50 | - | - |
| Calendar period of diagnosis in 2000-2009 | 2.97 (0.98–8.96) | 0.05 | 2.81 (0.92–8.61) | 0.07 |
UC, ulcerative colitis; HR, hazard ratio; CI, confidence interval; BMI, body mass index.