Table 5.
Primary and secondary outcomes by tumor type
| Tumor type | ICH | Median CTCAE | Major bleed | Minor bleed | Recurrent thrombosis |
|---|---|---|---|---|---|
| Primary brain tumors | |||||
| GBM | 5 | 3 | 10 | 14 | 1 |
| Glioma | 4 | 1 | 5 | 2 | 0 |
| Meningioma | 0 | N/A | 1 | 1 | 0 |
| CNS lymphoma | 1 | 1 | 2 | 3 | 1 |
| Metastatic tumors | |||||
| Lung | 1 | 3 | 1 | 3 | 0 |
| Breast | 1 | 1 | 1 | 0 | 1 |
| Renal | 0 | N/A | 0 | 0 | 0 |
| Ovary | 1 | 1 | 1 | 0 | 0 |
| Uterine | 0 | N/A | 0 | 0 | 0 |
| Melanoma | 1 | 3 | 1 | 0 | 0 |
Abbreviations: CNS, central nervous system; CTCAE, Common Terminology Criteria for Adverse Events; GBM, glioblastoma multiforme; ICH, intracranial hemorrhage; N/A, not applicable.