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. 2021 Apr 22;12:638556. doi: 10.3389/fphar.2021.638556

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Copyright © 2021 Zhao, Liu, Liu, Peng, Huang, Li, Wang, Xu, Sun, Qi, Ling, Li, Zhang, Mao and Qu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of HDIVC on the time to negative nucleic acid load. The overall negative probability of nasopharyngeal swab (A) and stool (C) at admission between the HDIVC and control groups were compared and no significant difference was found. The time to negative nucleic acid was compared between HDIVC and control groups for nasopharyngeal swab (B), median [IQR], days, 14 [8, 21] vs 13 [7, 21], P = 0.79) and for stool (D), median [IQR], days, 12 [7, 17] vs 13 [10, 20], P = 0.12). HDIVC, high dose intravenous vitamin C; COVID-19, coronavirus disease 2019. IQR, interquartile range.