Table 1.
Demographic and biochemical characteristics between COPD patients and control subjects
| Variables | COPD (n=180) | Control (n=180) | P |
|---|---|---|---|
| Age (years) | 74.0 (68.5, 82.0) | 67.0 (50.3, 79.6) | 0.437 |
| Male, n (%) | 132 (73.2) | 114 (63.2) | 0.351 |
| Hospital stay (day) | 10.0 (7.0, 14.0) | N.S. | N.S. |
| WBC (109/L) | 6.79 (5.07, 9.52) | 5.32 (4.32, 6.93) | <0.01 |
| Neutrophils (109/L) | 4.74 (3.38, 7.22) | 3.15 (2.21, 3.96) | <0.01 |
| Lymphocyte (109/L) | 1.08 (0.78, 1.45) | 2.15 (1.72, 2.63) | <0.01 |
| Monocyte (109/L) | 0.47 (0.33, 0.68) | 0.35 (0.29, 0.44) | <0.05 |
| CRP (μg/mL) | 88.3±9.6 | 36.5±7.4 | <0.01 |
| TNF-α (ng/mL) | 103.5±7.9 | 30.3±6.2 | <0.01 |
| IL-6 (pg/mL) | 48.6±10.6 | 19.6±7.6 | <0.05 |
| MCP-1 (pg/mL) | 206.5±42.5 | 58.6±7.6 | <0.01 |
| FVC (L) | 1.88 (1.36, 2.47) | N.S. | N.S. |
| FEV1 (%) | 40.4 (27.6, 64.8) | N.S. | N.S. |
| FEV1/FVC (%) | 51.3 (43.3, 58.5) | N.S. | N.S. |