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Knockdown of GRP94 reduced the expression of ETV1 and MAPK pathway proteins in CRC cells. (a) ETV1 expression level in GRP94-KD DLD-1 cells was detected by QPCR and (b) Western blotting (n=3). (c) Silencing GRP94 caused decreased level of p38, p-p38, ERK, p-ERK, JNK, and p-JNK in MAPK pathway (n=3). All experiments were repeated at least three times and calculated as mean±SD. (****p<0.0001)
