Table 2.
Bivariate associations with daily delirium (n = 883).
| Overall (n = 883) | No delirium (n = 722) | Delirium (n = 161) | p-value | |
|---|---|---|---|---|
| Transplant day | 0.007 | |||
| Median [IQR] | 12 (3–25) | 11 (3–23) | 16 (6–31) | |
| Location | 0.726 | |||
| Transplant unit | 818 (92.6%) | 666 (92.2%) | 152 (94.4%) | |
| PICU | 62 (7.0%) | 53 (7.3%) | 9 (5.6%) | |
| Other | 3 (0.3%) | 3 (0.4%) | 0 (0%) | |
| Supplemental oxygen | <0.001 | |||
| Yes | 102 (11.6%) | 67 (9.3%) | 35 (21.7%) | |
| No | 781 (88.4%) | 655 (90.7%) | 126 (78.3%) | |
| Blood product transfusion | 0.589 | |||
| Yes | 328 (37.1%) | 265 (36.7%) | 63 (39.1%) | |
| No | 555 (62.9%) | 457 (63.3%) | 98 (60.9%) | |
| Medication exposures in prior 24 h | ||||
| Anticholinergics | 555 (62.9%) | 459 (63.6%) | 96 (59.6%) | 0.368 |
| Antiepileptics | 118 (13.4%) | 85 (11.8%) | 33 (20.5%) | 0.005 |
| Antipsychotics | 98 (11.1%) | 70 (9.7%) | 28 (17.4%) | 0.008 |
| Benzodiazepines | 463 (52.4%) | 378 (52.4%) | 85 (52.8%) | 0.931 |
| Melatonin | 77 (8.7%) | 52 (7.2%) | 25 (15.5%) | 0.002 |
| Opiates | 526 (59.6%) | 424 (58.7%) | 102 (63.4%) | 0.288 |
| Steroids | 249 (28.2%) | 173 (24.0%) | 76 (47.2%) | <0.001 |
| Daily transplant therapy | ||||
| Cyclosporine | 192 (21.7%) | 155 (21.5%) | 37 (23.0%) | 0.673 |
| Defibrotide | 136 (15.4%) | 115 (15.9%) | 21 (13.0%) | 0.4 |
| Eculizumab | 10 (1.1%) | 8 (1.1%) | 2 (1.2%) | 0.999 |
| Methotrexate | 24 (2.7%) | 22 (3.0%) | 2 (1.2%) | 0.286 |
| Mycophenolate Mofetil | 146 (16.5%) | 113 (15.7%) | 33 (20.5%) | 0.159 |
| Sirolimus | 48 (5.4%) | 43 (6.0%) | 5 (3.1%) | 0.18 |
| Tacrolimus | 177 (20.0%) | 130 (18.0%) | 47 (29.2%) | 0.002 |
| Total body irradiation | 4 (0.5%) | 4 (0.6%) | 0 (0%) | 0.999 |