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. 2021 Apr 27;5(4):417–430. doi: 10.7150/ntno.59568

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Quantitative analysis of RPV and EuS in mouse tissues 5 days post-dosing. (A) NRPV drug concentration was measured in various tissues by UPLC-MS. (B) Europium-153 concentration was quantitated by ICP-MS. (C) Gamma-ray emission from collected tissues was measured after briefing radioactive decay by scintillation counting. (C) Raw radioactivity was divided by total radioactivity in all tissue measured per animal, giving percent injected dose, which was further normalized against tissue weight (% ID/g). (D) Pearson correlation between NRPV drug concentration values and europium-153 was determined in day 5 spleen samples.