Table 3.
Hazard Ratios and corresponding confidence intervals for smokers vs non-smokers (ATS Milan 2019).
| Incidence (*10000) | Smoker | Pack-Years | Chi-square for trend | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Number of cases | Exp | Non Exp | No | Ex | Yes | <10 | 10-19 | 20-29 | >30 | ||
| Oral cavity | 112 | 1.97 | 0.85 | 1* |
1,10 (0.65-1.87) |
2.63 (1.72-4.01) |
1.31 (0.40-4.23) |
2.21 (1.07-4.54) |
1.71 (0.73-4.01) |
4.88 (2.94-8.11) |
0.19 |
| Oesophagus | 33 | 0.59 | 0.25 | 1* | 1.41 (0.55-3.59) |
3.09 (1.37-6.96) |
0(0-) | 1.13 (0.15-8.74) |
3.53 (1.00-12.51) |
5.90 (2.33-14.96) |
0.26 |
| Stomach | 225 | 2.48 | 2.105 | 1* | 1.03 (0.72-1.46) |
1.52 (1.10-2.11) |
0.84 (0.31-2.29) |
1.17 (0.61-2.24) |
1.39 (0.75-2.59) |
2.08 (1.32-3.28) |
0.46 |
| Colon & Rectum | 1080 | 11.03 | 10.34 | 1* | 1.16 (1.00-1.35) |
1.30 (1.11-1.51) |
1.56 (1.12-2.18) |
1.30 (0.99-1.71) |
1.33 (1.00-1.76) |
1.13 (0.86-1.47) |
0.015 |
| Liver | 143 | 1.33 | 1.403 | 1* | 0.84 (0.54-1.30) |
1.15 (0.75-1.76) |
n.a.** | 1.14 (0.53-2.48) |
1.60 (0.80-3.18) |
0.80 (0.35-1.84) |
0.76 |
| Gallbladder | 114 | 1.33 | 1.05 | 1* | 1.17 (0.73-1.87) |
1.54 (0.97-2.43) |
1.19 (0.37-3.82) |
1.78 (0.84-3.76) |
0.99 (0.36-2.73) |
2.05 (1.07-3.91) |
0.33 |
| Pancreas | 309 | 3.77 | 2.79 | 1* | 1.18 (0.89-1.58) |
1.69 (1.29-2.21) |
1.39 (0.71-2.73) |
1.50 (0.92-2.46) |
1.56 (0.94-2.58) |
1.93 (1.29-2.89) |
0.067 |
| Larynx | 29 | 0.965 | 0.098 | 1* | 8.31 (1.66-41.43) |
34.81 (8.07-150.14) |
12.37 (2.22-68.92) |
13.51 (3.31-55.12) |
18.79 (4.98-70.98) |
22.76 (6.75-76.80) |
0.0019 |
| Bronchus and lung | 829 | 21.14 | 4.54 | 1* | 3.07 (2.49-3.78) |
8.48 (7.09-10.14) |
1.17 (0.64-2.15) |
3.73 (2.81-4.95) |
5.90 (4.60-7.57) |
12.03 (9.99-14.49) |
<.0001 |
| Skin cancers (including melanoma) | 1429 | 11.48 | 14.51 | 1* | 1.07 (0.94-1.22) |
0.90 (0.78-1.04) |
0.78 (0.53-1.13) |
1.04 (0.81-1.33) |
1.04 (0.80-1.35) |
0.85 (0.66-1.09) |
0.47 |
| Breast | 2952 | 28.21 | 28.77 | 1* | 0.91 (0.83-0.99) |
0.96 (0.87-1.05) |
0.97 (0.98-0.78) |
0.88 (0.74-1.05) |
1.12 (0.95-1.33) |
0.99 (0.85-1.16) |
0.036 |
| Cervix uteri | 62 | 0.965 | 0.504 | 1* | 1.91 (1.02-3.59) |
2.51 (1.38-4.57) |
1.71 (0.40-7.28) |
2.76 (1.12-6.81) |
2.70 (1.03-7.11) |
2.48 (1.01-6.08) |
0.019 |
| Corpus uteri | 428 | 3.77 | 4.26 | 1* | 0.75 (0.58-0.96) |
0.82 (0.64-1.06) |
0.74 (0.39-1.40) |
0.91 (0.58-1.40) |
0.72 (0.43-1.21) |
0.98 (0.66-1.46) |
0.015 |
| Ovary | 273 | 2.297 | 2.74 | 1* | 1.04 (0.78-1.34) |
0.88 (0.64-1.21) |
1.12 (0.58-2.19) |
0.83 (0.46-1.49) |
0.98 (0.54-1.75) |
0.43 (0.20-0.92) |
0.91 |
| Kidney | 167 | 1.56 | 1.64 | 1* | 1.10 (0.75-1.60) |
1.11 (0.74-1.65) |
1.41 (0.62-3.25) |
0.39 (0.12-1.24) |
1.02 (0.47-2.12) |
1.41 (0.79-2.52) |
0.58 |
| Bladder. urinary tract | 170 | 3.63 | 1.12 | 1* | 2.37 (1.56-3.60) |
5.67 (3.96-8.14) |
2.53 (1.01-6.35) |
3.06 (1.59-5.87) |
6.87 (4.21-11.21) |
7.40 (4.79-11-45) |
<.0001 |
| Brain and nervous system | 123 | 1.485 | 1.21 | 1* | 1.44 (0.94-2.21) |
1.18 (0.74-1.91) |
1.12 (0.35-3.58) |
1.26 (0.54-2.92) |
1.84 (0.88-3.86) |
0.69 (0.25-1.90) |
0.09 |
| Thyroid | 159 | 1.56 | 1.54 | 1* | 0.89 (0.60-1.32) |
0.92 (0.61-1.37) |
1.12 (0.48-2.56) |
0.95 (0.47-1.89) |
0.76 (0.33-1.73) |
0.68 (0.32-1.47) |
0.53 |
| Lymphomas | 298 | 3.26 | 2.79 | 1* | 1.20 (0.90-1.59) |
1.37 (1.03-1.83) |
1.57 (0.85-2.90) |
1.30 (0.77-2.18) |
1.62 (0.99-2.65) |
1.08 (0.64-1.81) |
0.12 |
| Multiple myeloma | 115 | 1.103 | 1.12 | 1* | 1.02 (0.64-1.62) |
1.15 (0.71-1.85) |
1.36 0.49-3.77) |
1.52 (0.72-3.21) |
0.89 (0.32-2.45) |
1.20 (0.55-2.62) |
0.86 |
| All leukaemia | 128 | 0.919 | 1.33 | 1* | 1.22 (0.81-1.85) |
0.85 (0.52-1.41) |
0.63 (0.15-2.60) |
1.42 (0.68-2.97) |
0.20 (0.03-1.42) |
0.74 (0.30-1.84) |
0.43 |
| All neoplasms | 9487 | 112.09 | 90.96 | 1* | 1.38 (1.31-1.45) |
1.10(1.04-1.16) | 1.07 (0.94-1.21) |
1.19 (1.09-1.31) |
1.41 (1.29-1.55) |
1.63 (1.51-1.76) |
<.0001 |