Table 3.
The 15 splicing factors differentially expressed in pancreatic cancer.
| Gene | Five GEO datasets | TCGA combined GTEx datasets | ||||
|---|---|---|---|---|---|---|
| log2FC | P value | Adjusted p value | log2FC | P value | Adjusted p value | |
| ELAVL2 | 7.75 | 6.38E-12 | 7.98E-12 | 619.73 | 1.93E-05 | 2.41E-05 |
| ELAVL4 | -65.99 | 4.09E-35 | 3.07E-34 | 2675.26 | 0.003551 | 0.004098 |
| ESRP1 | 407.94 | 1.29E-25 | 3.86E-25 | 73705.38 | 6.95E-17 | 1.16E-16 |
| HNRNPA0 | 186.84 | 1.12E-14 | 1.53E-14 | 68273.36 | 4.83E-42 | 1.03E-41 |
| HNRNPL | -59.93 | 9.84E-12 | 1.14E-11 | 43150.39 | 2.33E-17 | 4.36E-17 |
| HNRNPM | 12.71 | 0.099515 | 0.099515 | 111358.08 | 2.73E-61 | 6.83E-61 |
| HNRNPU | -98.38 | 2.23E-07 | 2.39E-07 | 19590.14 | 0.353961 | 0.379244 |
| NOVA1 | 28.82 | 8.53E-26 | 3.20E-25 | 388.42 | 0.654919 | 0.654919 |
| RBM4 | 69.88 | 4.53E-26 | 2.26E-25 | 98766.58 | 1.70E-86 | 5.09E-86 |
| RBM5 | -414.03 | 5.09E-37 | 7.63E-36 | -77494.35 | 1.25E-86 | 4.67E-86 |
| RBMX | 30.34 | 4.02E-23 | 1.01E-22 | -171121.44 | 1.92E-100 | 1.44E-99 |
| SF1 | -89.17 | 7.94E-23 | 1.70E-22 | -91532.75 | 5.38E-15 | 8.07E-15 |
| SFPQ | 330.84 | 2.40E-19 | 4.51E-19 | -181385.34 | 1.94E-08 | 2.65E-08 |
| TRA2A | 113.27 | 1.92E-15 | 2.87E-15 | -1377268.74 | 3.74E-88 | 1.87E-87 |
| YBX1 | -698.48 | 8.45E-18 | 1.41E-17 | 1480274.26 | 2.32E-118 | 3.49E-117 |