Table 3.
Multiple ordinal logistic regression analysis for association between the progression of ESCC and all metabolites.
| Metabolites | β | Std. Error | t value | p value | OR (95% CI) |
|---|---|---|---|---|---|
| Dopamine | -0.213 | 0.099 | -2.157 | 3.10E-02 | 0.81 ( 0.67 ~ 0.98 ) |
| L-Histidine | -0.365 | 0.101 | -3.601 | 3.17E-04 | 0.69 ( 0.57 ~ 0.85 ) |
| 5-Hydroxyindoleacetate | -0.230 | 0.094 | -2.463 | 1.38E-02 | 0.79 ( 0.66 ~ 0.95 ) |
| L-Tryptophan | -0.056 | 0.096 | -0.582 | 5.60E-01 | 0.95 ( 0.78 ~ 1.14 ) |
| PC(14:0/0:0) | 0.179 | 0.136 | 1.322 | 1.86E-01 | 1.20 ( 0.92 ~ 1.56 ) |
| PC(O-16:1/0:0) | -0.251 | 0.103 | -2.425 | 1.53E-02 | 0.78 ( 0.64 ~ 0.95 ) |
| PE(18:0/0:0) | -0.231 | 0.120 | -1.920 | 5.49E-02 | 0.79 ( 0.63 ~ 1.00 ) |
| PC(16:1/0:0) | -0.212 | 0.135 | -1.573 | 1.16E-01 | 0.81 ( 0.62 ~ 1.05 ) |
| Hypoxanthine | 0.366 | 0.084 | 4.372 | 1.23E-05 | 1.44 ( 1.22 ~ 1.70 ) |
| PC(18:2/0:0) | -0.106 | 0.101 | -1.053 | 2.92E-01 | 0.90 ( 0.74 ~ 1.10 ) |
| Inosine | 0.348 | 0.085 | 4.106 | 4.02E-05 | 1.42 ( 1.20 ~ 1.67 ) |
| Carnitine(14:1) | 0.065 | 0.089 | 0.729 | 4.66E-01 | 1.07 ( 0.90 ~ 1.27 ) |
| Glycochenodeoxycholate | 0.258 | 0.085 | 3.037 | 2.39E-03 | 1.29 ( 1.10 ~ 1.53 ) |
| 2'-O-methylcytidine | -0.154 | 0.117 | -1.312 | 1.90E-01 | 0.86 ( 0.68 ~ 1.08 ) |
| PC(P-18:0/18:3) | 0.144 | 0.081 | 1.771 | 7.66E-02 | 1.16 ( 0.98 ~ 1.36 ) |