Table 6.
HLA genotype predictors of infection. Common HLA in the control group was used as a reference genotype to assess the relative risk at p < 0.05.
| Control | COVID-19 infected | RR (95% CI) | p-value | |
|---|---|---|---|---|
| A*02a A*01 A*26 |
17 (26.3) 14 (5.2) 27 (10.0) |
65 (24.1) 33 (12.2) 13 (4.8) |
1.0 1.47 (1.14–1.90) 0.68 (0.42–1.10) |
– 0.011 0.104 |
| B*51a B*07 B*56 B*57 |
52 (19.3) 18 (6.7) 0 (0.0) 1 (0.4) |
47 (17.4) 8 (3.0) 10 (3.7) 8 (3.0) |
1.0 0.65 (0.35–1.20) 2.11 (1.71–2.59) 1.87 (1.37–2.55) |
– 0.182 0.001 0.032 |
| C*07a C*01 C*16 |
53 (19.6) 4 (1.5) 22 (8.1) |
64 (23.7) 12 (4.4) 9 (3.3) |
1.0 1.37 (0.99–1.90) 0.53 (0.30–0.94) |
– 0.178 0.015 |
| DRB1*04a DRB1*08 |
74 (27.4) 2 (0.7) |
44 (16.3) 13 (4.8) |
1.0 2.32 (1.71–3.16) |
– <0.001 |
RR: Relative risk.
CI: Confidence interval.
a
Reference category.