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. 2021 May 6;22:139. doi: 10.1186/s13059-021-02330-1

Fig. 2.

Fig. 2

Statistical metrics of molecular haplotype linkage between variants at different genomic distance extracted from linked-reads and Hi-C sequencing data of RPE-1 (a,c,e) and NA12878 (b,d,f) cells. a, b Fraction of linked variants. c, d Average number of links between linked variants. e, f Fraction of links consistent with cis linkage. The residual linkage in the linked-reads data ∼50% accuracy (e and f) reflects tagging of unrelated DNA fragments from both parental homologs by the same molecular barcodes by chance