13.9. Analysis.

Comparison 13: Additional data tables, Outcome 9: Trials of topical zinc

Trials of topical zinc
Study	Intervention	Results	Outcomes
Khattar 2007	20% zinc oxide vs 15% SA/LA	There were similar cure rates for zinc oxide and SA/LA	Cure rate in 8/22 vs 8/22 at 3 months. Adverse events included erythema (10 vs 17), swelling (12 vs 5), scaling (7 vs 14), blackening (4 vs 2), and the SA/LA group also had itching and tenderness
Sharquie 2007	10% zinc sulphate vs 5% zinc sulphate vs placebo	There were higher cure rates for zinc sulphate compared to placebo	Cure in 7/16 (44%) vs 4/29 (14%) vs 1/22 (5%) at 6 months. Adverse events were only experienced in the zinc sulphate group, and this included 7 cases of itching or pain and 6 cases of postinflammatory hypopigmentation