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. 2012 Sep 12;2012(9):CD001781. doi: 10.1002/14651858.CD001781.pub3

Felt 1998.

Study characteristics
Methods This study was carried out in a secondary care setting, and it was open.
Intention‐to‐treat analysis was not carried out.
This study was conducted in the USA.
Participants 61 participants were recruited: 10 dropped out.
Inclusion criteria of the trial
  • Children

  • Ordinary warts

  • Warts anywhere

Interventions
  • Relaxation imagery

  • SA

  • No treatment

Outcomes Outcomes of the trial
  1. Cure at 6 to 18 months

Notes Only 1 index wart was treated in each child.
A quote on page 134 related to performance bias: "A similar percentage of children across experimental groups reported use of topical treatments after the initial 8 weeks."
The authors commented that "spontaneous regression within 2 years is thought to occur for about half to two thirds of warts"; yet, they used 6 to 18 months as the timeframe for follow up.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Random assignment was conducted by picking a study number from a hat. (page 132)
Comment: This was probably adequate.
Allocation concealment (selection bias) Unclear risk It was unclear if any attempt was made to conceal allocation.
Blinding of participants and personnel (performance bias)
All outcomes High risk No attempt was made at blinding.
Blinding of outcome assessment (detection bias)
All outcomes High risk No attempt was made at blinding.
Incomplete outcome data (attrition bias)
All outcomes Low risk 51/61 participants completed. Dropouts were distributed across groups. The reasons for dropout were not given.
Comment: This was probably adequate.
Selective reporting (reporting bias) Unclear risk All outcomes were reported.