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. 2021 May 6;12:61. doi: 10.1186/s40104-021-00581-3

Table 6.

Effects of exogenously introduced SCFAs on the mRNA abundances for key factors associated with glucose metabolism in longissimus dorsi of GF pigs a

Items GF FA P-value
FOXO-1 1.00 ± 0.44 1.35 ± 0.34 0.20
Sirt1 1.00 ± 0.02 0.86 ± 0.03 0.11
INSR 1.00 ± 0.09 0.99 ± 0.21 0.97
INS1 1.00 ± 0.15 1.08 ± 0.09 0.64
PIK3 1.00 ± 0.09 0.96 ± 0.07 0.73
GSK3 1.00 ± 0.04 1.01 ± 0.08 0.91

a GF germ-free, FA short-chain fatty acids, FOX-1 foxo1 forkhead box O1, Sirt1 silent information regulator 1, INSR insulin receptor, IRS1 insulin receptor substrate 1, PIK3 phosphatidylinositol 3-kinase catalytic subunit type 3, GSK3 glycogen synthase kinase 3. Values are means ± SEMs, n = 6/group