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. 2021 May 5;20:47. doi: 10.1186/s12944-021-01473-1

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© The Author(s) 2021

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Fig. 2 — a Haematoxylin-eosin staining (5x). Skin sample from the upper part of the back. Deep dermis. The collagen bundles are coarse and separated by apparently empty spaces. Note the overview in the insert in the upper corner. b Hale’s colloidal iron staining (5x). Back skin. Deep dermis. The same area as the H&E staining. Between the coarse collagen fibres, the accumulated mucopolysaccharides appear blue. Note the overview in the insert in the upper corner