Table 2.
Performance of each group on memory tests and biomarker data
| Unimpaired carriers | Non-carriers | Carriers versus Non-carriers | |||||||
|---|---|---|---|---|---|---|---|---|---|
| n = 19 | n = 26 | ||||||||
| Median | IQR | Median | IQR | U | p-value | Effect size (r) | |||
| Memory Test (z scores) | |||||||||
| ROCF-pr | 0.21 | −1.02 | 0.71 | 0.18 | −0.92 | 0.67 | 240.00 | .87 | − |
| CERAD-m | 0.48 | −0.71 | 1.17 | 0.64 | 0.3 | 1.28 | 196.00 | .24 | - |
| Visual-Verbal composite | 0.33 | −0.48 | 0.94 | 0.65 | 0.05 | 0.87 | 215.00 | .46 | |
| Biomarkers | |||||||||
| Cortical Amyloid (DVR) | 1.51 | 1.34 | 1.74 | 1.12 | 1.08 | 1.16 | 17.00 | < .001 | .79 |
| Entorhinal Tau (SUVR) | 1.48 | 1.12 | 1.77 | 1.03 | 0.97 | 1.15 | 98.00 | < .001 | .51 |
| Inferior Temporal Tau (SUVR) | 1.28 | 1.19 | 1.32 | 1.19 | 1.05 | 1.27 | 157,00 | .04 | .31 |
Note: Values are expressed as median and interquartile range (IQR).
ROCF: Rey-Osterrieth Complex Figure test. ROCF-pr: ROCF percent retention. CERAD: Consortium to Establish a Registry for Alzheimer’s Disease. CERAD-m: CERAD word list memory Test.
DVR: distribution volume ratio; SUVR = standardized uptake value ratio.
U: Mann-Whitney U test.
p values were calculated through Mann-Whitney U test.