Table 5.

Baseline Characteristics by PEM Status

Parametera	All subjects	PEM-positive	PEM-negative	P value for difference between PEM-positive and PEM-negativeb
	n = 68	n = 40	n = 28
Age	9.2 (7.2, 10.8)	9.1 (7.0, 10.5)	9.9 (7.4, 11.6)	0.51
HT-SDS	−3.3 (−4.5, −2.5)	−2.6 (−3.1, −2.2)	−4.6 (−5.3, −3.8)	<0.00001
Pretreatment Height Velocity (cm/year)	4.0 (3.2, 4.6)	4.3 (3.7, 4.8)	3.3 (2.8, 4.4)	0.02
Difference between chronological and bone age	2.3 (1.6, 4.1)	1.9 (0.9, 2.8)	4.0 (2.1, 5.0)	<0.001
Standard GH stimulation test result (ng/mL)	5.4 (1.8, 7.6)	7.1 (5.1, 8.8)	1.7 (1.3, 3.5)	<0.0001

Abbreviations: GH, growth hormone; HT-SDS, height standard deviation score; PEM, Predictive Enrichment Marker

^amedians and interquartile ranges

^b P value for difference between PEM-positive an PEM-negative groups by one-way ANOVA