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. 2021 Apr 22;8:636670. doi: 10.3389/fvets.2021.636670

Table 11.

Component variables explaining variability in antimicrobial drugs (AMD) in preweaned dairy calves on California dairies.

Identified components Variation Percent (%) Component variables Correlation
1. Change in the use of antimicrobial drugs following 37.13 Antimicrobials used on solid feed 0.670
the implementation of Veterinary Feed Directive Antimicrobials used in water 0.633
(VFD) in 2017 Injectable antimicrobials 0.629
Antimicrobials used in milk or milk replacer 0.623
Producer considers AMD importance in raising calves 0.521
Antibiotic drug costs since VFD final rule 0.477
Started use of alternatives to antimicrobials 0.475
2. Use of diagnostics to guide treatment decision 18.60 Submission of calves to diagnostic labs 0.674
Use of diagnostic techniques to guide treatment 0.491
Frequency of animal health monitoring by veterinarian 0.468
3. Source of information and decision on AMD for 17.95 Decision to use injectable or oral antimicrobials (Vet/Non-vet)a 0.618
feed, milk, water, oral, and injectable Source of information on antimicrobials (Vet/ Non-vet)a 0.582
Decision to use any antimicrobials (Vet/Non-vet)a 0.573
Method of estimating the drug dosage (Vet/Non-vet)a 0.552
Decision to treat on 1st day of illness (Vet/Non-vet)a 0.548
Decision on second choice antimicrobial (Vet/Non-vet)a 0.510
4. Antimicrobial use protocols and records 17.64 Estimation treatment duration for any antimicrobial (Label/Others) 0.613
Tracked treatment information (Date/Route/Dose/None) 0.574
Estimation of treatment duration for injectable antimicrobials (Label/Others) 0.506
Tracked antibiotic withdrawal interval (Yes/No) 0.446
Treatment protocols components (Vaccinations/Disease Definition/Treatment) 0.432
Method of tracking treatments (Computer/Paper/Hutch/Memory/Chalk) 0.436
Keep drug inventory log (Yes/No) 0.425
5. Common drugs to treat pneumonia and diarrhea 11.06 First choice antibiotic for treatment of Pneumonia (1-florfenicol, 2- 3rd generation cephalosporins, 3-Tulathromycin, Gamithromycin and Tildipirosin, 4-Oxytetracycline, 5-Pencillin and Ampicillin, 6-Tylosin, 7-Enrofloxacin) 0.511
6. Calf feed management 16.70 Milk fed to preweaned calves (Pasteurized/ Not) 0.642

The multiple factor analysis identified six components with 25 component variables with correlation >0.40 at the first three dimensions. The first three dimensions of MFA explained 21.46% of the variability (dimension 1 = 9.75%; dimension 2 = 6.56%; dimension 3 = 5.15%).

a

Varaibility due to veterinarian making decision compared to non-veterinarian.