Table 3.
Levels of inflammatory markers
| Lab result - median (IQR) | Missing data | All patients | BMI <18.5 | BMI 18.5–24.9 | BMI 25–29.9 | BMI 30–34.9 | BMI ≥35 | p-value |
|---|---|---|---|---|---|---|---|---|
|
n=82 (a) |
n=814 (b) |
n=1162 (c) |
n=809 (d) |
n=369 (e) |
||||
| IL-6 | 1956 | 38.1 (16–80) | 45.7 (22.4–89.1) | 43.4 (18.6–91.7) | 39.5 (16.9–85.9) | 35.5 (14.6–73.5) | 34.2 (13.2–71.6) | 0.714 |
| CRP - initial | 543 | 10.6 (4.6–18.6) | 9.2 (4.2–18.3) | 9.6 (4.2–18.2) | 11.7 (5.5–19.9)d | 9.4 (4.3–17.3)c | 11.2 (5–18.9) | 0.013 |
| CRP - maximum | 23 | 11.5 (2.9–22.5) | 10.2 (2.9–19.4) | 10.1 (2.2–21.1) | 13 (3.4–23.1) | 11.2 (2.8–22) | 11.6 (3.3–23.3) | 0.053 |
| CRP - final | 547 | 5.8 (2.5–13.1) | 6.6 (3–16.5) | 6 (2.8–14.2) | 6.2 (2.6–13.7) | 5.4 (2.1–12.15) | 5(2.1–11.2) | 0.316 |
| WBC - initial | 281 | 7.2 (5.5–9.9) | 7.5 (5.9–11.2)cde | 7.2 (5.4–10.6) | 7.4 (5.6–10.2)a | 7 (5.3–9.4)a | 7.3 (5.4–9.5)a | <0.001 |
| Neutrophils - initial | 283 | 5.5 (3.8–8) | 5.7 (4.2–8.9) | 5.6 (3.8–8.8)de | 5.6 (4.1–8.3)d | 5.2 (3.7–7.5)bc | 5.5 (3.8–7.5)b | <0.001 |
| Lymphocytes - initial | 282 | 1 (0.7–1.4) | 0.8 (0.6–1.3)bcde | 0.9 (0.6–1.3)a | 1 (0.7–1.3)a | 1 (0.7–1.4)a | 1.1 (0.7–1.4)a | 0.005 |
(1) p-values refer to ANOVA, and the letters denote the columns with which a statistically significant pairwise comparison exists (Bonferroni’s method); (2) BMI in kg/m2, IL-6 in pg/mL, CRP in mg/dL, WBC in 103/μL, neutrophils 103/μL, lymphocytes in 103/μL
BMI body mass index, IQR interquartile range, CRP C-reactive protein, IL-6 interleukin, WBC white blood cell count