Table 4.

Female fertility and litter data of F0 and F1 (cohort 1B)

Dietary dose (mg/kg bw per day)	F0				F1 (cohort 1B)
	Control	100	300	1,000	Control	100	300	1,000
No. of females paired	24	24	24	24	20	20	20	20
No. of females mated	24	24	24	24	20	19	18	17
No. of females pregnant	24	23	22	22	20	19	17	17
Live litters	24	23	21	21	20	19	17	16
Total litter loss	0	0	1	1	0	0	0	1
Mean oestrous cycle duration (days)	4.6	4.5	4.5	4.4	4.4	4.4	4.2	4.5
Precoital interval > 4 daysa	0	1	1	1	2	0	3	0
Duration of pregnancy > 23 daysa	0	1	1	1	0	0	0	0
Mean duration of pregnancy (days)	22.6	22.7	22.8	22.9	22.6b	22.6b	22.3b	22.5b
Implantation sites/dam	14.7	15.5	15.6	15.3	15.6	16.0	16.2	15.3
Total number of implantation sites	294	309	311	306	311	304	275	260
Post‐implantation loss	38	24	48	30	20	29	16	28
Post‐implantation loss (mean per dam, %)	17.5	8.1	17.0	11.8	6.7	10.1	6.0	12.8
Litters with > 2 post‐implantation lossesa	4	3	9	4	2	3	1	3
Live litters with > 1 stillborna	0	1	0	1	0	0	0	0
Live litter size	12.7	14.3	13.5	13.7	14.6b	14.4b	15.3b	13.7b
Litter weight at birth	87.3	97.5	95.3	94.6	97.7b	97.2b	97.2b	96.4b

^aCalculated by the Panel based on individual data.

^bCalculated by the Panel based on individual data and including all 21 pregnant animals with live litters in the study.