Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 1;32(7):622–633. doi: 10.1091/mbc.E20-06-0394

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Mohan et al. “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology.

This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License.

PMC Copyright notice

FIGURE 9: — Illustration depicting signaling mechanism of IgG3(+) autoantibodies (AAb) generated against human β1AR. (A) Agonist-mediated β1AR signaling. (B) Antagonist-mediated β1AR signaling. (C) Agonist-mediated β1AR signaling modulated by IgG3(+) AAb. (D) Antagonist-mediated β1AR signaling modulated by IgG3(+) AAb.