. Author manuscript; available in PMC: 2021 Aug 28.

Published in final edited form as: ACS Appl Nano Mater. 2020 Aug 7;3(8):8037–8051. doi: 10.1021/acsanm.0c01506

Table 1.

Surface markers of each particular cell type

Cell Types	Full Name	Phenotype
CD45	Leukocytes	CD45⁺
NOS monocytic cells	Not otherwise specified monocytic cells	CD45⁺CD11b⁺ Ly6G⁻
NOS granulocytic cells	Not otherwise specified granulocytic cells	CD45⁺CD11b⁺ Ly6G⁺
G-MDSCs	Granulocytic myeloid-derived suppressive cells	CD45⁺CD11b⁺Ly6G⁺ Ly6C⁻MHCII⁻CD86⁻
M-MDSCs	Monocytic myeloid-derived suppressive cells	CD45⁺CD11b⁺Ly6G⁻Ly6C⁺MHCII⁻SSClow
TINs	Tumor-infiltrating neutrophils	CD45⁺CD11b⁺Ly6G⁺MHCII⁺CD86⁺
QNs	Quiescent neutrophils	CD45⁺CD11b⁻Ly6G⁺
Activated DCs	Activated dendritic cells	CD45⁺CD11b⁺CD11c⁺MHCII⁺CD86⁺
Inactive DCs	Inactive dendritic cells	CD45⁺CD11b⁺CD11c⁺MHCII⁻CD86⁺, CD45⁺CD11b⁺CD11c⁺MHCII⁺CD86⁻, or CD45⁺CD11b⁺CD11c⁺MHCII⁻CD86⁻
NK cells	Natural killer cells	CD45⁺CD11b⁺NK1.1⁺Ly6G⁻Ly6C⁻ F4/80⁻
M1 macrophages	Type 1 tumor-associated macrophages	CD45⁺CD11b⁺F4/80⁺Ly6G⁻Ly6C⁻MHCII⁺CD86⁺
M2 macrophages	Type 2 tumor-associated macrophages	CD45⁺CD11b⁺F4/80⁺Ly6G⁻Ly6C⁻MHCII⁻CD86⁻
NOS TAMs	Not otherwise specified tumor-associated macrophages	CD45⁺CD11b⁺F4/80⁺Ly6G⁻Ly6C⁻MHCII⁺CD86⁻, or CD45⁺CD11b⁺F4/80⁺Ly6G⁻Ly6C⁻MHCII⁻CD86⁺