Table 3.

Assessment of HRQoL in CKD patients: the questionnaires most commonly used

Generic questionnaires	Content
Karnofsky Performance Scale Index [41]	A scale assessing functional impairment scoring using three states (conditions) that describe different levels of performance from 100 (normal state) to 0 (dead): A (100–80%): Able to carry on normal activity and to work. No special care is needed. B (70–50%): Unable to work. Able to live at home, care for most personal needs. A varying degree of assistance is needed. C (40–0%): Unable to care for self. Requires equivalent of institutional or hospital care. Disease may be progressing rapidly
Nottingham Health Profile [42]	38 items to measure six dimensions: physical mobility, energy, emotional reactions, sleep, pain and social isolation
SF-36 [43]	36 items in eight domains with two composite scores: PCS and mental composite score (MCS) and a question about self-evaluation of change in health during the past year (reported health), which does not belong to any score or dimension or the total SF-36 score
Sickness Impact Profile [44]	136 items to measure 12 dimensions: sleep and rest, eating, work, home management, recreation and pastimes, ambulation, mobility, body care and movement, social interaction, alertness behaviour, emotional behaviour and communication
Schedule for Evaluation of Individual Quality of Life [45]	Interview-based instrument that focuses on the domains and factors that determine each patient’s quality of life
Disease-specific questionnaires
KDQOL Questionnaire [46]	36-item health survey with multi-item scales targeted at concerns of individuals with kidney disease and on dialysis
KDQOL-SF [47]	43 kidney disease–targeted items and 36 items that provide a measure of physical and mental health. Three composite scores (PCS, MCS and kidney disease component summary score)
Parfrey Test [48]	24 items with two dimensions (physical and emotional)