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. 2021 Apr 22;13(17):8224–8234. doi: 10.1039/d0nr08285f

Fig. 2. (a) Macrophage viability after 2.5 h treatment (0.5 mg ml−1 NPs, 100 μg ml−1 gentamicin) quantified by ATP generation. BG and especially Ag compromise macrophage viability. (b) Macrophage toxicity quantified by LDH release, which indicates membrane damage. In line with viability measurements, Ag-containing particles express toxicity towards macrophages. The red exclamation point indicates the interference of silver with the LDH assay (compare Fig. S5). Control PBS was set as 100% viability and 0% toxicity. Significance levels compared to PBS are shown, p < 0.0001. N = 3.

Fig. 2