Table I.

Effect of Indomethacine on Weight, Plasma K⁺, and Plasma Renin Activity in Patients on Enalapril or Felodipine

	Enalapril	Felodipine	p value Felodipine vs. Enalapril
Change in weight (kg)	0.8± 0.3*	0.4±0.2	0.15
Change in creatinine (mmol/L)	0.03± 0.01*	0.02±0.01	0.6
Change in K+ (mmol/L)	0.24± 0.04*	0.12±0.04*	0.04
Change in plasma renin activity (pmol angiotensin I/mL/h)	−3.7†± 1.1*	−0.36†±0.11*	<0.05
Percent fall in plasma renin activity	33	22	0.3
Values are means±SEM. *p<0.05; †initial values were E=11.1 and F=1.64 pmol angiotensin I/mL/h