Table II.

Effect of Indomethacin on Weight, Plasma K⁺, Creatinine, Plasma Renin Activity, and Aldosterone in Patients Taking Enalapril or Amlodipine

	Enalapril	Amlodipine	p Value Enalapril vs. Amlodipine
Wt (kg)	0.9±0.4*	0.9±0.3*	0.9
K+ (mmol/L)	0.09±0.08	0.19±0.05*	0.4
Creatinine (mmol/L)	0.00±0.01	0.00±0.01	0.9
Change in plasma renin activity (pmol angiotensin I/mL/h)	−3.7±1.1*	−0.29±0.09*	<0.05
Percent fall in plasma renin activity	−56%	−15%	<0.05
Aldosterone (pmol/L)	70±26*	2±35	0.1
Values are means±SEM. *p<0.05