Table.
Effects of Statins on Blood Pressure Control in Normotensives and Hypertensives: Clinical Trial Results
| Author | Patients | Variable | Effects of Statins |
| Sung et al., 1997 26 | NBP | SBP response to stress | Significantly reduced |
| Resting SBP | Not significantly reduced | ||
| Muramatsu et al., 1997 31 | NBP | Resting SBP, DBP | Unchanged |
| Antonicelli et al., 1990 32 | NBP | Resting SBP, DBP | Unchanged |
| Kool et al., 1995 33 | NBP | Resting SBP | Unchanged |
| Leibovitz et al., 2001 50 | NBP | Resting SBP, DBP | Significantly reduced |
| Jarai et al, 1996 27 | U‐HBP | Resting SBP, DBP | Significantly reduced |
| Straznicky et al., 1995 28 | U‐HBP | SBP and DBP response to | Significantly reduced |
| A‐II, NE | Unchanged | ||
| Abetel et al., 1998 29 | U‐HBP | Resting SBP, DBP | Significantly reduced |
| D'Agostino et al., 1993 30 | T‐HBP† | Resting SBP,DBP | Unchanged |
| Borghi et al., 2001 34 | T‐HBP*† | Resting SBP, DBP | Significantly reduced |
| Glorioso et al., 1999 35 | U‐HBP Resting | SBP, DBP, PP, | Significantly reduced |
| MBP response to CPT | Significantly reduced | ||
| Tonolo et al., 2000 36 | T‐HBP+NIDDM | Resting SBP, DBP | Significantly reduced |
| Velussi et al., 1999 37 | T‐HBP+NIDDM | Resting SBP, DBP | Significantly reduced SBP |
| Sposito et al., 1999 38 | T‐HBP* | Resting SBP, DBP | Significantly reduced |
| Borghi et al., 2000 39 | T‐HBP* | Resting SBP, DBP, MBP, PP | Significantly reduced |
| Nazzaro et al., 1999 40 | U‐HBP | Resting SBP, DBP | Significantly reduced |
| Mugen et al., 2000 48 | HBP | Resting SBP, DBP | Significantly reduced |
| Ferrari et al., 2001 49 | T‐HBP | 24‐hour SBP | Significantly reduced |
| NBP, HBP=normotensive, hypertensive patients; SBP/DBP=systolic/diastolic blood pressure; U=untreated; A‐II=angiotensin II; NE=norephinephrine; T=treated; PP=pulse pressure; MBP=mean blood pressure; CPT=cold pressor test; NIDDM=non‐insulin‐dependent diabetes; *uncontrolled; †well controlled | |||