Table 2. Dietary intakes of participants with RTT and unaffected controls.
| Features | Group of Individuals* | p-value | |
|---|---|---|---|
| RTT | C | ||
| Dietary Source | |||
| Number of subjects | 44 | 21 | - |
| Food (%) | 73 | 100 | 0.001 |
| Formula (%) | 75 | 0 | 0.001 |
| Multivitamins and/or mineral supplements (%) | 75 | 24 | 0.001 |
| Dietary Intake | |||
| Number of participants | 41 | 19 | - |
| Macronutrients | |||
| Energy (kcal/d) | 1313 (433, 2402) | 1659 (878, 2035) | 0.05 |
| Fat (% E) | 34 (18, 85) | 35 (26,50) | NS |
| Carbohydrate (% E) | 52 (4, 70) | 50 (25, 62) | NS |
| Protein (g/d) | 44 (21, 108) | 56 (23, 91) | NS |
| B-Complex Vitamins | |||
| Thiamine (mg/d) | 0.9 (0, 3.8) | 1.2 (0.5, 2.7) | NS |
| Riboflavin (mg/d) | 2.2 (0.6, 9.7) | 1.3 (0.7, 3.9) | 0.01 |
| Niacin (mg/d) | 28 (13, 94) | 27 (14, 45) | NS |
| Folate (mcg/d) | 333 (0, 963) | 314 (92,630) | NS |
| Cobalamin (mcg/d) | 6.1 (1.3, 15.9) | 3.0 (1.3, 10.2) | 0.001 |
| Fiber (g/day) | 6.2 (3.4, 26.9) | 11.1 (3.4, 26.9) | 0.01 |
| Amino Acids | |||
| Tryptophan (g/day) | 0.60 (0, 1.7) | 0.61 (0.3, 1.1) | NS |
| Leucine (g/day) | 4.11 (0.1, 9.1) | 4.30 (2.2, 6.5) | NS |
| Methionine (g/day) | 1.12 (0, 2.4) | 1.31 (0.8, 2.0) | NS |
| Phenylalanine (g/day) | 1.87 (0.1, 4.5) | 2.33 (1.2, 3.9) | NS |
| Tyrosine (g/day) | 1.72 (0, 3.7) | 1.92 (1.0, 3.0) | NS |
| Glutamate (g/day) | 8.16 (0, 19.4) | 9.89 (5.8, 15.2) | 0.04 |
| Plasma amino acids | |||
| Leucine (μmol/L) | 81 (40, 222) | - | - |
| Methionine (μmol/L) | 20 (8, 69) | - | - |
| Phenylalanine (μmol/L) | 45 (25, 87) | - | - |
| Tyrosine (μmol/L) | 56 (27, 167) | - | - |
| Glutamate (μmol/L) | 36, (12, 89) | - | - |
| Glutamine (μmol/L) | 567 (295, 856) | - | - |
*RTT, Rett; C, control group. Values expressed as median (minimum, maximum) or proportion (%). Mann-Whitney test (continuous variables) or Chi-squared test (discrete variables), p-value <0.05 considered significant.