Table 1. Human and chimpanzee brain region-specific regDMRs.
| Brain structure | Species | Gene | Gene name | Hyper or hypo* |
|---|---|---|---|---|
| DLPFC | Human | PAQR4 KREMEN2 | progestin and adipoQ receptor family member 4 kringle containing transmembrane protein 2 | hyper |
| MYLK | myosin light chain kinase | hypo | ||
| ADAM30 | ADAM metallopeptidase domain 3 | mix | ||
| MLST8 | MTOR associated protein, LST8 homolog | hypo | ||
| TMEM177 | transmembrane protein 177 | hyper | ||
| TRIM65 | tripartite motif containing 65 | hyper | ||
| C10orf71 & C10orf71-AS1 | chromosome 10 open reading frame 71 | hyper | ||
| FAM193A | family with sequence similarity 193 member A | hypo | ||
| SLC13A4 | solute carrier family 13 member 4 | hyper | ||
| Chimp-anzee | LRCH1 | leucine rich repeats and calponin homology domain containing 1 | hyper | |
| CUGBP1 | CUGBP Elav-like family member 1 | hyper | ||
| Cerebellum | Human | GP5 | glycoprotein V platelet | hyper |
| CHAD ACSF2 | chondroadherin acyl-CoA synthetase family member 2 | hypo | ||
| SEPP1 | selenoprotein P | hyper | ||
| DLEU7 | deleted in lymphocytic leukemia 7 | hyper | ||
| HRH1 | histamine receptor H1 | hyper | ||
| PARVG | parvin gamma | hypo | ||
| TRAF3IP2 | TRAF3 interacting protein 2 | hypo | ||
| SH3BGR | SH3 domain binding glutamate rich protein | hyper | ||
| FAM83A | family with sequence similarity 83 member A | hypo | ||
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | hypo | ||
| DLGAP1 & DLGAP1-AS1/FLJ35776 | DLG associated protein 1 | hypo | ||
| PLCH1 | phospholipase C eta 1 | hypo | ||
| FAM198B | golgi associated kinase 1B | hypo | ||
| TRAF3IP2 | TRAF3 interacting protein 2 | hypo | ||
| STK33 | serine/threonine kinase 33 | hypo | ||
| CCDC8 | coiled-coil domain containing 8 | hypo | ||
| GSTO2 | glutathione S-transferase omega 2 | hypo | ||
| CRIP3 | cysteine rich protein 3 | mix | ||
| CPNE6 | copine 6 | hypo | ||
| PHACTR1 | phosphatase and actin regulator 1 | hypo | ||
| FUT4 | fucosyltransferase 4 | hypo | ||
| MEDAG | mesenteric estrogen dependent adipogenesis | mix | ||
| MIR192 & MIR194-2 | microRNA 192 microRNA 194–2 |
hypo | ||
| MIR1182 & FAM89A | microRNA 1182 family with sequence similarity 89 member A | hyper | ||
| DNAH10 | dynein axonemal heavy chain 10 | hyper | ||
| SDR42E1 | short chain dehydrogenase/reductase family 42E, member 1 | hyper | ||
| LOC101928322 | CELF2 divergent transcript | hypo | ||
| DMPK | DM1 protein kinase | hyper | ||
| Chimp-anzee | CCDC140 | CCDC140 long non-coding RNA | hyper | |
| CCDC102A | coiled-coil domain containing 102A | hyper | ||
| LINGO3 | leucine rich repeat and Ig domain containing 3 | hypo | ||
| ZNF608 | Zinc finger protein 68 | hyper | ||
| MYO18A | myosin XVIIIA | hypo | ||
| CDK15 | cyclin dependent kinase 15 | hypo | ||
| TRIM66 | tripartite motif containing 66 | hyper | ||
| SLC43A3 | solute carrier family 43 member 3 | hypo | ||
| ADAM32 | ADAM metallopeptidase domain 32 | hypo | ||
| SYTL1 | synaptotagmin like 1 | hyper | ||
| TCF21 | transcription factor 21 | hyper | ||
| BNC1 | basonuclin 1 | hyper | ||
| RNPEPL1 | arginyl aminopeptidase like 1 | hypo | ||
| APPL2 | adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 | hyper | ||
| GYPC | glycophorin C (Gerbich blood group) | hyper | ||
| DRD2 | dopamine receptor D2 | hypo | ||
| NODAL | nodal growth differentiation factor | hyper | ||
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | hyper | ||
| LRRC8D | leucine rich repeat containing 8 VRAC subunit D | hyper | ||
| TWIST2 | twist family bHLH transcription factor 2 | hyper | ||
| AVEN & CHRM5 | apoptosis and caspase activation inhibitor cholinergic receptor muscarinic 5 | hypo | ||
| LPL | lipoprotein lipase | hypo | ||
| KCNE3 | potassium voltage-gated channel subfamily E regulatory subunit 3 | hyper |
*Hypermethylated or hypomethylated