Table 2. Significantly changed metabolic clusters corresponding anatomic/functional regions.

AAL Region	TD Labels	BA (large to small)	Cluster (voxels)	T (Peak)	Z (Peak)	Peak Coordinates (x, y, z)
Frontal_Mid_R	Middle Frontal Gyrus	9, 46, 8, 10, 6, 44, 45	1740	-6.69	-6.2	44, 32, 28
Frontal_Mid_L	Middle Frontal Gyrus	9, 46, 6, 10, 8, 44, 45	1459	-6.2	-5.79	-46, 24, 26
Angular_R	Angular Gyrus	40, 39, 19, 2, 3, 18, 7, 1	1247	-6.08	-5.7	44, -64, 36
Parietal_Inf_L	Supramarginal Gyrus	40, 39, 19, 7	760	-5.89	-5.54	-52, -50, 38
Temporal_Mid_R	Middle Temp Gyrus	21, 20, 37, 22, 19	625	-5.39	-5.11	62, -40, -8
ParaHippocampal_L	Uncus	28, 34, 36	696	5.78	5.45	-24, 0, -32
Brainstem_R			183	4.92	4.71	14, -26, -22
Amygdala_R	Sub-Gyral		215	4.82	4.62	30, 2, -16

AAL: automated anatomical labeling. TD Labels: automated Talairach atlas labeling. BA: Brodmann area (areas with at least five voxles are listed). Signs of T or Z value: negative indicates hypo-metabolic changes; positive denotes hyper-metabolic changes.