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. 2021 Apr 26;17(4):e1009545. doi: 10.1371/journal.ppat.1009545

Fig 3. RNA transcripts from vertebrates are CpG-suppressed.

Fig 3

(A) Open reading frames (ORFs) from several organisms belonging to the indicated phyla were collected from the NCBI nucleotide database and dinucleotide frequency ratio (observed/expected) was calculated and frequency distribution for each dinucleotide in ORFs was plotted. (B) Average dinucleotide observed/expected ratio in various animal species. Evolutionary distance (presented in million years, Ma) of indicated species was based on [36]. (C) Average dinucleotide observed/expected ratio in various portions of vertebrate mRNA transcripts vertebrates.