Table 1.
Participant Characteristics in Study Populations
| Development (N=5017) N (%) or Mean (SD) | External Validation (N=2245) N (%) or Mean (SD) | |
|---|---|---|
| Age, years | 55.7 (15.9) | 52.8 (12.8) |
| <40 | 893 (17.8) | 331 (14.7) |
| 40–65 | 2689 (53.6) | 1570 (69.9) |
| >65 | 1435 (28.6) | 344 (15.3) |
| Female | 2198 (43.8) | 652 (29.0) |
| Black people | 1934 (38.6) | 539 (24.0) |
| BMI, kg/m2 | 29.0 (6.1) | 27.5 (5.4) |
| <20 | 131 (2.6) | 82 (3.7) |
| 20-<25 | 1212 (24.2) | 692 (30.9) |
| 25-<30 | 1870 (37.3) | 878 (39.2) |
| ≥30 | 1804 (36.0) | 588 (26.3) |
| Diabetes | 1296 (27.4) | 731 (34.7) |
| Measured GFR, ml/min/1.73m2 | 58.1 (29.7) | 83.2 (27.4) |
| <30 | 858 (17.1) | 52 (2.3) |
| 30-<60 | 2091 (41.7) | 414 (18.4) |
| 60-<90 | 1387 (27.7) | 846 (37.7) |
| ≥90 | 681 (13.6) | 933 (41.6) |
| Creatinine, mg/dL | 1.6 (0.9) | 1.1 (0.5) |
| Cystatin C, mg/L | 1.5 (0.6) | 1.2 (0.5) |
| B2M, mg/L | 3.8 (2.3) | 2.6 (1.5) |
| BTP, mg/L | 1.2 (0.8) | 0.8 (0.4) |
Development includes initial development and internal Validation (Figure S1). B2M, Beta 2-Microglobulin; BTP, Beta-Trace Protein.
Note: Values for categorical variables are given as number (percentage), for continuous variables, mean (standard deviation)