Figure 7.

Simulated temperatures in 20 patients for 220 kHz continuous wave (CW) or pulsed ultrasound (US) with 15-cycle pulses at either 62.5% duty cycle or 33.3% duty cycle. Temperature was calculated using the bioheat transfer equation. A heating source was determined from the time-averaged intensity derived from the acoustic pressure (eq.4). The maximum temperature after 400 s was reported in four regions: (a) extracranial soft tissue (ST), (b) bone, (c) brain, and (d) clot. Statistically significant differences between insonification schemes are denoted by asterisks ** : p < 0.01, **** : p < 0.0001).