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. 2021 Apr 28;2021:6619870. doi: 10.1155/2021/6619870

Figure 1.

Figure 1

The expression of MRC2 measured in the peripheral blood of 21 healthy subjects and 21 patients with DN detected by qRT-PCR increased in patients with DN (a). MRC2 expression in cell and animal models of DN and MRC2 silencing. The MRC2 expression in MMCs cultured under low-glucose and high-glucose conditions was detected using western blotting (b) and qRT-PCR (c). The MRC2 expression in the renal tissues of normal and DN mice was detected using western blotting (d) and qRT-PCR (e). The MRC2 expression in MMCs transfected with the negative control (si-NC) and siRNAs (si-MRC2 1 and si-MRC2 2) was detected using western blotting (f) and qRT-PCR (g). ∗∗∗P < 0.001 vs. healthy group. ∗∗P < 0.01, ∗∗∗P < 0.001 vs. control group.