. 2021 Feb 20;12(1):199–228. doi: 10.1016/j.jcmgh.2021.02.004

Table 2.

Gene Responsiveness to the Indicated Combinations of Δ(90), YAP^S127A, and L30P/R34P

Name of gene	Mouse gene ID	Human gene ID	Expression in HBs: fold change vs liver				Association with shortened survival in human cancers^a, ^b, ^c
Name of gene	Mouse gene ID	Human gene ID	Δ(90)+ YAP^S127A	Δ(90)+ L30P/R3P	YAP^S127A+ L30P/R3P	Δ(90)+ YAP^S127A+ L30P/R3P
Slc22a7	108114	10864	–25.69	–7.41	–13.99	–109.62	KIRC,^b LIHC^b
Inmt	21743	11185	–10.55	–5.52	–3.85	–31.22	LIHC^b
Gas1	14451	2619	–6.98	–3.76	–6.84	–22.76	THCA,^a KIRC,^a KIRP,^a KICH,^a COAD,^a READ,^a STAD^a
Atp5k^d	11958	521	–2.28	–1.89	–5.73	–11.40
Ttr^d	22139	7276	–5.35	–2.71	–3.31	–9.42
Cmtm8	70031	152189	–2.67	–1.95	–1.98	–6.14	KIRC,^b KIRP^b
Ppdpf^d	66496	79144	–2.16	–1.89	–2.51	–3.74	KIRP,^b KICH^b
Camkk2^d	207565	10645	–1.69	–1.66	–1.79	–3.51
Tmem65^d	74868	157378	2.08	1.82	1.99	2.95	UCEC^a
Tpm1^d	22003	7168	2.69	2.05	2.52	3.50	BLCA^a
Tgfa^d	21802	7039	2.12	2.33	2.62	3.98	PAAD,^a THCA^a
Tmpo^d	21917	7112	2.91	1.67	2.71	4.25	KIRP,^a KICH^a
Gars^d	353172	2617	2.86	1.68	2.01	4.57	KIRC,^a KIRP,^a KICH,^a BLCA,^a LIHC,^a BRCA^a
Rock2^d	19878	9475	2.77	2.83	3.08	5.22	KIRC,^b KIRP,^a KICH^a
Il22ra1^d	230828	58985	3.15	3.80	3.40	6.58
Arhgef2^d	16800	9181	4.93	1.86	4.45	8.72	KIRC,^a KICH,^a LIHC^a
Acot9^d	56360	23597	8.89	2.39	7.67	13.02	LIHC^a
Pck2	74551	5106	6.95	2.22	6.22	15.99	LIHC^a
Lgals3	16854	3958	7.06	2.34	8.42	18.40
Uap1l1^d	227620	91373	15.51	6.65	16.40	23.67	LIHC,^a PAAD^b
Serpine1	18787	5054	7.35	9.25	11.86	43.70	KIRC,^a KIRP,^a KICH,^a LIHC,^a STAD,^a HNSC^a
Igfbp1	16006	3484	58.42	12.80	31.41	132.32	KIRC,^a LUAD,^a STAD^a

NOTE. The 22 transcripts listed here are a subset of the original 41 “BYN” groups depicted in Figure 5F that remained after eliminating those that were not regulated in the same direction in each case or that were not also deregulated in tumors driven by other types of β-catenin mutations or in tumors arising from myc-/- and/or chrebp-/- hepatocytes.²²

Up-regulated.

Down-regulated.

See Figure 6 for Kaplan-Meier survival curves.

Also deregulated by Δ(90)+YAP^S127A+WT-NFE2L2 tumors.