Table 2. CEUS parameters before and after NAC for discriminating between good and minor responders.
| Pre-NAC | Post-NAC | Percent changes | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Good responders | Minor responders | P values | Good responders | Minor responders | P values | Good responders | Minor responders | P values | |||
| Diameter (mm) | 41.71±16.47 | 39.19±12.75 | 0.643 | 26.24±13.02 | 35.53±9.90 | 0.021* | −35.50±17.14 | −20.49±8.90 | 0.012* | ||
| IMAX (a.u.) | 4,608±13,569 | 3,947±3,070 | 0.235 | 1,297±2,264 | 2,913±4,141 | 0.015* | −46.44±34.70 | −5.8±29.00 | 0.008* | ||
| RT (s) | 12.58±1.85 | 16.57±1.21 | 0.564 | 14.32±2.35 | 17.10±2.98 | 0.432 | 2.57±27.41 | 9.58±33.27 | 0.322 | ||
| TTP (s) | 19.34±2.21 | 18.53±3.05 | 0.325 | 26.54±5.56 | 21.83±4.56 | 0.223 | 20.36±35.93 | 6.70±9.59 | 0.026* | ||
| mTT (s) | 35.96±43.49 | 31.96±11.22 | 0.712 | 35.79±30.68 | 42.24±28.20 | 0.643 | 19.15±54.04 | 40.32±38.39 | 0.657 | ||
Values are presented as means ± SD. P values for difference were determined by Student’s t-test or Mann-Whitney U test. Statistically significant differences (P<0.1). CEUS, contrast-enhanced ultrasound; NAC, neoadjuvant chemotherapy; IMAX, maximum intensity; RT, rise time; TTP, time to peak; mTT, mean transit time.