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. 2021 Apr;10(4):1418–1430. doi: 10.21037/gs-21-84

Figure 1.

Figure 1

LINC00511 was highly expressed in breast cancer. (A,B) Hierarchical cluster analysis of differential gene expression between cancer and normal tissues in the two breast cancer microarray datasets (FC >1.5, P<0.05, the red to green color gradient indicates the level of gene expression from high to low). (C) Overlapping ncRNAs with upregulated in the breast cancer cohorts GSE29431 and GSE42568 by VENNY (http://bioinfogp.cnb.csic.es/tools/venny/). (D,E,F,G,H,I,J) Seven overlapping ncRNAs were screened using the GEPIA database (http://gepia.cancer-pku.cn/index). (K) Expression of LINC00511 validated in breast cancer and paired normal tissues by qRT-PCR (N=96). (L) Upregulated expression of LINC00511 in breast cancer cell lines validated by qRT-PCR. *, P<0.05; **, P<0.01; ***, P<0.001; ****, P<0.0001. LINC00511, long intergenic non-protein coding ribonucleic acid 00511; ncRNA, non-coding ribonucleic acid; FC, fold change; GEPIA, Gene Expression Profiling Interactive Analysis; qRT-PCR, quantitative reverse transcription polymerase chain reaction.