Figure 5.

High expression of LINC00511 is corrected with drug resistance and prognosis in breast cancer. (A) LINC00511 was positively related to the half maximal inhibitory concentration (IC50) of Panobinostat: HDAC (N=27) in breast cancer cells. (B) Breast cancer patients with low LINC00511 expression had a longer OS in HMUCH. (C) Breast cancer patients with low LINC00511 had a longer OS in TCGA. (D,E,F,G) TCGA data showed that high LINC00511 expression resulted in worse OS, DSS, PFI, and DFI in pan-cancer. HDAC, histone deacetylase; OS, overall survival; DSS, disease specific survival; PFI, progression free interval; DFI, disease free interval; HMUCH, Harbin Medical University Cancer Hospital; TCGA, the cancer genome atlas.