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. 2020 Oct 15;40(5):1789–1798. doi: 10.1007/s10067-020-05458-w

Table 2.

AEs from csDMARD use

Participants
Rheumatologist-estimated N = 100
  AE rate in patients using various csDMARDs (%), median (IQR)
    MTX 15.0 (20.0)
    LEF 15.0 (10.0)
    SASP 10.0 (10.0)
    HCQ 10.0 (5.0)
Patient-reported N = 400
  Experienced AEs after taking prescribed csDMARD, n (%)
    MTX (n = 202) 80 (39.6)
    LEF (n = 172) 58 (33.7)
    SASP (n = 35) 17 (48.6)
    HCQ (n = 55) 8 (14.6)
  Changed csDMARD, n (%) 113 (28.3)
  Notified rheumatologist about AEs, n (%)a 116 (85.9)

AE adverse event, csDMARD conventional synthetic disease-modifying antirheumatic drug, HCQ hydroxychloroquine, IQR interquartile range, LEF leflunomide, MTX methotrexate, SASP salazosulfapyridine

an = 135