Table 2:
Lung disease | No. at risk | No. with grade 3 PGD (%) |
Univariate | Multivariable* | ||||
---|---|---|---|---|---|---|---|---|
OR | 95% CI | P value | OR | 95% CI | P value | |||
IPF | 501 | 145 (28.9) | Ref. | - | - | Ref. | - | - |
CTD-ILD | 101 | 33 (32.7) | 1.19 | 0.75-1.88 | 0.45 | 1.12 | 0.64-1.97 | 0.69 |
Multivariable model is adjusted for age at transplant, sex, race (Caucasian, Black, or other), body mass index, lung allocation score, intraoperative mean pulmonary arterial pressure, type of transplant (single or bilateral), use of intraoperative cardiopulmonary bypass or extracorporeal membrane oxygenation, and pre-transplant corticosteroid use and includes transplant center as a random effect.
Abbreviations: PGD = primary graft dysfunction; OR = odds ratio; CI = confidence interval; IPF = idiopathic pulmonary fibrosis; CTD-ILD = connective tissue disease-associated interstitial lung disease.