Table 3.
Timeline and characteristics of PROSE use
Case 1 | Case 2 | Case 3R | Case 3L | |
---|---|---|---|---|
Duration of daytime PROSE use prior to development of PED | 2.5 years | 0 | 20+ years | 20+ years |
Duration of PED prior to continuous wear PROSE | 2 weeks | 6 weeks | 2 weeks | 2 weeks |
Duration of continuous wear PROSE use prior to culture | 10 days | 3 weeks | Few weeks* | 1 week |
Timepoint of sustained improvement of PED/Duration of continuous wear PROSE treatment until endpoint | NA/1 week (defect progressed to perforation) | 6 days/2 weeks (defect healed) | 1 week/12 weeks (defect healed) | 5 days/7 weeks (defect healed) |
exact amount of time is not known
PROSE = prosthetic replacement of the ocular surface ecosystem, PED = persistent epithelial defect