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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Cornea. 2021 Jun 1;40(6):774–779. doi: 10.1097/ICO.0000000000002696

Table 3.

Timeline and characteristics of PROSE use

Case 1 Case 2 Case 3R Case 3L
Duration of daytime PROSE use prior to development of PED 2.5 years 0 20+ years 20+ years
Duration of PED prior to continuous wear PROSE 2 weeks 6 weeks 2 weeks 2 weeks
Duration of continuous wear PROSE use prior to culture 10 days 3 weeks Few weeks* 1 week
Timepoint of sustained improvement of PED/Duration of continuous wear PROSE treatment until endpoint NA/1 week (defect progressed to perforation) 6 days/2 weeks (defect healed) 1 week/12 weeks (defect healed) 5 days/7 weeks (defect healed)
*

exact amount of time is not known

PROSE = prosthetic replacement of the ocular surface ecosystem, PED = persistent epithelial defect