Table 4.

Antimicrobial activity of compounds 1–28 isolated from E. subumbrans roots and twigs.

Compound	MIC (μg/mL)
	Gram-positive bacteria					Gram-negative bacteria					Fungi
	EF	MT	MRSA	SA	SP	SF	PA	ST	STR	EC	CA
1	Inactive	Inactive	Inactive	Inactive	Inactive	Inactive	128	128	128	128	Inactive
2	Inactive	Inactive	Inactive	Inactive	Inactive	Inactive	128	Inactive	Inactive	128	Inactive
3	Inactive	Inactive	Inactive	Inactive	Inactive	Inactive	128	Inactive	128	128	Inactive
4	Inactive	Inactive	Inactive	Inactive	Inactive	Inactive	128	128	Inactive	128	Inactive
5	Inactive	Inactive	Inactive	Inactive	Inactive	Inactive	128	128	Inactive	128	Inactive
6	128	Inactive	32	Inactive	Inactive	128	128	128	Inactive	128	128
7	128	128	128	64	128	128	128	128	Inactive	128	128
8	128	128	128	64	128	Inactive	128	128	Inactive	128	128
9	2	2	4	2	2	Inactive	128	128	Inactive	Inactive	4
10	8	8	8	64	8	128	128	Inactive	128	Inactive	16
11	128	128	64	64	64	Inactive	128	128	Inactive	Inactive	128
12	Inactive	Inactive	Inactive	128	Inactive	Inactive	128	128	Inactive	Inactive	Inactive
13	Inactive	Inactive	Inactive	128	Inactive	Inactive	128	128	Inactive	128	Inactive
14	128	128	64	32	64	Inactive	128	128	Inactive	128	128
15	Inactive	Inactive	Inactive	128	Inactive	128	128	Inactive	Inactive	128	Inactive
16	Inactive	Inactive	Inactive	128	Inactive	Inactive	128	Inactive	Inactive	128	Inactive
17	Inactive	Inactive	Inactive	128	Inactive	Inactive	128	Inactive	Inactive	Inactive	Inactive
18	Inactive	Inactive	Inactive	128	Inactive	Inactive	128	128	Inactive	128	Inactive
19	Inactive	Inactive	128	128	64	Inactive	128	Inactive	Inactive	128	128
20	128	Inactive	Inactive	16	Inactive	Inactive	Inactive	Inactive	Inactive	Inactive	16
21	Inactive	Inactive	Inactive	Inactive	Inactive	Inactive	128	Inactive	Inactive	Inactive	Inactive
22	Inactive	Inactive	Inactive	128	128	128	128	Inactive	Inactive	128	Inactive
23	Inactive	Inactive	Inactive	128	Inactive	Inactive	128	Inactive	Inactive	128	Inactive
24	Inactive	Inactive	128	128	128	Inactive	128	128	Inactive	128	128
25	Inactive	128	Inactive	128	128	128	128	128	128	Inactive	Inactive
26	Inactive	Inactive	Inactive	Inactive	Inactive	Inactive	128	Inactive	Inactive	Inactive	Inactive
27	Inactive	Inactive	Inactive	Inactive	Inactive	Inactive	128	Inactive	Inactive	Inactive	Inactive
28	Inactive	Inactive	Inactive	Inactive	Inactive	Inactive	128	Inactive	Inactive	Inactive	Inactive
Vancomycin	2	2	1	0.5	2	-	-	-	-	-	4
Gentamicin	-	-	-	-	-	4	4	1	0.5	4	-

Inactive at >128 μg/mL. EF = Enterococcus faecalis (ATCC 29212); MT = Micrococcus luteus (DMST 15503); MRSA = Methicillin Resistant Staphylococcus aureus (NPRC 001R); SA = Staphylococcus aureus (ATCC 25923); SP = Streptococcus pyogenes (ATCC, 19615); SF = Shigella flexneri (DMST 4423); PSA = Pseudomonas aeruginosa (ATCC 10145); STP = Salmonella typhi (DMST 22842); STM = Salmonella typhimurium (DMST 562); EC = Escherichia coli (TISTR 780); CA = Candida albicans (ATCC 10231).