Figure 2. Rpl11 haploinsufficient mice upregulate ribosomal protein genes in the earliest erythroid precursors.
A. GSEA enrichment levels for individual cells (BFU-E through basophilic erythroblasts) grouped according to clusters A-D from wildtype control mice, Flvcr1-deleted mice, and Rpl11 haploinsufficient mice shown as a false discover rate (FDR) plot for the KEGG ribosome pathway. B. Transcript expression levels (RPKM) of ribosomal protein genes in individual cells isolated from wildtype control and Flvcr1-deleted, and Rpl11 haploinsufficient mouse marrow grouped according to clusters A-D. Data is presented as mean ± SD. *: P ≤ 0.05; **: P ≤ 0.01; ***: P ≤ 0.001.