Table 2.
Cross-sectional correlations between fatigue and patient reported, clinical, laboratory and ultrasound variables at all visits in patients with rheumatoid arthritis initiating biologic DMARDs.
| Baseline, n = 208 | 1 month, n = 208 | 2 months, n = 204 | 3 months, n = 197 | 6 months, n = 183 | 12 months, n = 160 | |
|---|---|---|---|---|---|---|
| Patient’s global VAS | 0.73** | 0.76** | 0.70** | 0.70** | 0.76** | 0.66** |
| Joint pain VAS | 0.64** | 0.70** | 0.65** | 0.63** | 0.71** | 0.47** |
| MHAQ | 0.62** | 0.58** | 0.22* | 0.48** | 0.62** | 0.41** |
| SF36 Mental Health | − 0.56** | − 0.67** | − 0.55** | − 0.58** | − 0.61** | − 0.55** |
| Pain catastrophizing | 0.58** | 0.60** | 0.52** | 0.52** | 0.50** | 0.42** |
| 28 tender joint count | 0.48** | 0.50** | 0.47** | 0.51** | 0.54** | 0.26* |
| Examiner’s global VAS | 0.28** | 0.27** | 0.23* | 0.29** | 0.32** | 0.17* |
| Calprotectin (μg/L) | 0.07 | 0.14* | 0.08 | 0.02 | 0.18* | 0.11 |
| CRP (mg/L) | 0.11 | 0.13 | 0.09 | 0.09 | 0.14 | 0.02 |
| 28 swollen joint count | 0.15* | 0.08 | 0.09 | 0.09 | 0.10 | 0.01 |
| Sum score GS | 0.02 | 0.03 | 0.02 | 0.02 | 0.02 | 0.05 |
| Sum score PD | 0.03 | 0.05 | 0.01 | 0.03 | 0.02 | 0.01 |
VAS visual analogue scale, MHAQ modified health assessment questionnaire, SF36 Mental Health short form 36 Mental Health scale score, CRP C-reactive protein, GS grey scale ultrasound, PD power Doppler ultrasound
*p < 0.05, **p < 0.001